Multiple Sclerosis:

Multiple sclerosis (MS) is a chronic inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms, including physical, mental, and sometimes psychiatric problems. MS takes several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms). Between attacks, symptoms may disappear completely; however, permanent neurological problems often occur, especially as the disease advances. 

While the cause is not clear, the underlying mechanism is thought to be either destruction by the immune system or failure of the myelin-producing cells. Proposed causes for this include genetics and environmental factors such as infections. MS is usually diagnosed based on the presenting signs and symptoms and the results of supporting medical tests.

There is no known cure for multiple sclerosis. Treatments attempt to improve function after an attack and prevent new attacks. Medications used to treat MS while modestly effective can have adverse effects and be poorly tolerated. Many people pursue alternative treatments, despite a lack of evidence. The long-term outcome is difficult to predict, with good outcomes more often seen in women.

While many existing MS treatments modulate the disease’s symptoms, Genzyme introduced a once-daily oral treatment for relapsing forms of MS .This approved product is supported by a robust clinical program and has demonstrated significant efficacy in the three key measures for an MS treatment – reducing annualized relapse rate (ARR), delaying the progression of disability, and reducing MRI (magnetic resonance imaging) disease activity

Multiple sclerosis (MS) is a chronic inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged. This damage disrupts the ability of parts of the nervous system to communicate, resulting in a wide range of signs and symptoms, including physical, mental, and sometimes psychiatric problems. MS takes several forms, with new symptoms either occurring in isolated attacks (relapsing forms) or building up over time (progressive forms). Between attacks, symptoms may disappear completely; however, permanent neurological problems often occur, especially as the disease advances. 
While the cause is not clear, the underlying mechanism is thought to be either destruction by the immune system or failure of the myelin-producing cells. Proposed causes for this include genetics and environmental factors such as infections. MS is usually diagnosed based on the presenting signs and symptoms and the results of supporting medical tests.
There is no known cure for multiple sclerosis. Treatments attempt to improve function after an attack and prevent new attacks. Medications used to treat MS while modestly effective can have adverse effects and be poorly tolerated. Many people pursue alternative treatments, despite a lack of evidence. The long-term outcome is difficult to predict, with good outcomes more often seen in women.
While many existing MS treatments modulate the disease’s symptoms, Genzyme introduced a once-daily oral treatment for relapsing forms of MS .This approved product is supported by a robust clinical program and has demonstrated significant efficacy in the three key measures for an MS treatment – reducing annualized relapse rate (ARR), delaying the progression of disability, and reducing MRI (magnetic resonance imaging) disease activity

For more information go to: www.genzyme.com

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